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← Human Body & HealthA bacterial population treated with antibiotics exhibits increasing resistance. Which mechanism explains the rapid spread of resistance genes across diverse bacterial species within the gut microbiome?
A)Increased DNA replication fidelity
B)Horizontal gene transfer via plasmids✓
C)Epigenetic modifications to bacterial DNA
D)Enhanced ribosome proofreading efficiency
💡 Explanation
Horizontal gene transfer facilitates the swift dissemination of resistance genes because plasmids, carrying these genes, transfer between bacteria, rather than resistance arising solely from mutations within a single species. Therefore, plasmid-mediated transfer rapidly spreads resistance, rather than relying on slow, species-specific mutation and selection.
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