A weightlifter strains to complete a deadlift — which mechanism most directly stimulates muscle hypertrophy under high mechanical tension?

💡 Explanation

The mTOR (mechanistic target of rapamycin) signaling pathway is a primary regulator of protein synthesis and muscle growth; because mechanical tension activates this pathway, it leads to increased muscle protein synthesis and hypertrophy. Therefore, mTOR activation directly stimulates muscle growth, rather than affecting energy metabolism or waste buffering.

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