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← Human Body & HealthAn individual with iodine deficiency consumes excess cruciferous vegetables (e.g., broccoli, cabbage). Which consequence follows from the increased intake of glucosinolates?
A)Elevated TSH, suppressed T4 production
B)Goiter development, impaired thyroid hormone✓
C)Increased T4, suppressed TSH release
D)Enhanced iodine uptake, reduced goiter
💡 Explanation
Glucosinolates in cruciferous vegetables inhibit iodine uptake in the thyroid, further impairing thyroid hormone synthesis in iodine-deficient individuals and causing goiter development via hypertrophy and hyperplasia. This is because the thyroid stimulating hormone (TSH) continues stimulating the thyroid gland, therefore promoting growth rather than normal hormone production. The result is goiter.
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