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Human Body & Health

An IVF clinic administers GnRH agonists to patients undergoing ovarian stimulation. Which effect dominates due to pulsatile hormonal regulation?

A)Immediate LH surge suppression
B)Uncontrolled follicle maturation
C)Initial LH/FSH surge, then suppression
D)Direct ovarian hyperstimulation risk

💡 Explanation

The GnRH agonist initially stimulates LH and FSH release because it mimics GnRH's pulsatile action. This causes a surge before downregulating GnRH receptors, therefore the initial surge is the dominant effect, rather than immediate suppression or direct ovarian hyperstimulation.

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