As dopamine receptor sensitivity decreases in the nucleus accumbens of a cocaine user, which outcome follows regarding drug-seeking behavior?

💡 Explanation

Increased craving occurs in cocaine addiction because downregulation of dopamine receptors leads to reduced reward response, resulting in a greater need to stimulate the circuit despite tolerance. Therefore, craving intensifies, rather than euphoria increasing or the user stopping completely because withdrawal would initially intensify then gradually decline.

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