During chronic inflammatory bowel disease (IBD), what distinguishes the process of inflammation resolution from an acute response?

💡 Explanation

Inflammation resolution involves active mechanisms that promote tissue repair, rather than simply suppressing inflammation; it includes a switch from pro-inflammatory eicosanoids to pro-resolving mediators to reduce neutrophil recruitment. This class switching facilitates the resolution of inflammation, because it actively promotes healing, rather than merely reducing inflammatory signals.

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