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Human Body & Health

Following a booster vaccine dose, what distinguishes the response of memory B cells compared to the initial priming dose?

A)Reduced somatic hypermutation rate
B)Lower affinity antibody production
C)Faster differentiation into plasma cells
D)Exclusive IgM isotype antibody secretion

💡 Explanation

Memory B cells, after a booster, exhibit quicker activation and differentiation into plasma cells because they are pre-sensitized; therefore, a rapid antibody response is observed, rather than the slower initial response requiring more time for clonal selection and affinity maturation.

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