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Human Body & Health

Following prolonged hypoxia, which process results from macrophage 'efferocytosis'?

A)Reduced inflammatory cytokine production
B)Increased antigen presentation
C)Heightened T-cell activation threshold
D)Diminished neutrophil recruitment rate

💡 Explanation

Efferocytosis, the phagocytosis of apoptotic cells, signals resolution. Reduced inflammatory cytokine production follows because macrophages taking up dead cells release anti-inflammatory signals. Therefore, it promotes tissue repair rather than continued inflammation linked to inadequate clearance of dead cells.

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