If a burn wound disrupts keratinocyte migration due to compromised fibronectin matrix deposition in the extracellular matrix, which consequence follows, assuming the wound remains sterile?

💡 Explanation

Re-epithelialization requires keratinocyte migration across the wound bed, a process dependent on fibronectin matrix deposition. Because impaired fibronectin deposition reduces keratinocyte motility, the re-epithelialization process slows down. Therefore, delayed wound closure is the consequence, rather than increased inflammation or angiogenesis, which are separate processes.

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