If a mutation disables the EGFR receptor's ability to internalize after growth factor binding in lung cancer cells, which consequence follows?

💡 Explanation

Disabling EGFR internalization prevents receptor downregulation, leading to sustained signaling. Because the growth signal persists unchecked due to impaired receptor-mediated endocytosis, therefore uncontrolled cell proliferation occurs, rather than attenuation of the signal or activation of apoptotic pathways.

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