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Human Body & Health

If a novel virus evades initial immune detection due to a glycocalyx-mimicking capsid, which consequence follows regarding the adaptive immune response?

A)Immediate memory B-cell activation
B)Delayed T-cell mediated cytotoxicity
C)Accelerated complement cascade activation
D)Enhanced macrophage phagocytosis efficiency

💡 Explanation

Delayed T-cell mediated cytotoxicity results because the virus's glycocalyx-mimicking capsid prevents early recognition by pattern recognition receptors and subsequent antigen presentation, thus slowing T-cell activation. Therefore, a cytotoxic T cell response is delayed, rather than an immediate B-cell response, or enhanced phagocytosis; the complement cascade would also be less effective without initial antibody binding.

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