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Human Body & Health

If a pathogen expresses surface antigens nearly identical to a healthy cardiac protein, which consequence follows?

A)Enhanced T-cell activation threshold.
B)Decreased antibody-mediated cytotoxicity.
C)Elevated major histocompatibility complex I expression.
D)Autoimmune myocarditis via molecular mimicry.

💡 Explanation

Autoimmune myocarditis can arise when the immune system attacks the heart muscle, because molecular mimicry occurs when pathogen antigens resemble self-antigens. This leads to T cells attacking cardiac tissue rather than remaining tolerant; therefore, myocarditis develops, rather than immune tolerance being maintained.

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