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Human Body & Health

If a patient undergoing anesthesia experiences unexpected bronchospasm and hypotension after propofol administration, which immunological mechanism is most likely causing this patient's anaphylaxis?

A)Complement cascade activation by IgG
B)IgE-mediated mast cell degranulation
C)T-cell mediated cytokine storm
D)Direct drug-induced platelet aggregation

💡 Explanation

Anaphylaxis is often caused by IgE-mediated mast cell degranulation in response to an allergen, such as a drug. Therefore, the mast cells release histamine and other mediators causing bronchospasm and hypotension, rather than other immune responses being the primary cause.

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