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← Human Body & HealthIf a patient undergoing anesthesia suddenly develops bronchospasm and hypotension, which consequence follows the release of histamine from mast cells?
A)Increased cardiac output
B)Vasodilation and increased permeability✓
C)Increased systemic vascular resistance
D)Reduced airway resistance
💡 Explanation
Histamine release from mast cells during anaphylaxis induces systemic vasodilation and increased vascular permeability, because histamine binds to H1 receptors on endothelial cells. Therefore, blood pressure decreases rather than increasing vascular resistance, because the peripheral blood vessels dilate.
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