If a patient with chronic anemia experiences a sudden increase in 2,3-bisphosphoglycerate (2,3-BPG) levels, which consequence follows regarding oxygen delivery to tissues?

💡 Explanation

Increased 2,3-BPG in red blood cells reduces hemoglobin's affinity for oxygen because it stabilizes the T (tense) state of hemoglobin, therefore oxygen is more readily released to tissues. The Bohr effect shifts the oxygen dissociation curve to the right, rather than increasing affinity, which would reduce oxygen offloading.

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