If a patient with chronic anemia receives a blood transfusion using blood stored for an extended period, which consequence follows regarding oxygen delivery?

💡 Explanation

Extended storage of blood decreases 2,3-BPG levels in red blood cells; 2,3-BPG normally reduces hemoglobin's oxygen affinity. Because of this depletion, hemoglobin's affinity for oxygen increases, therefore oxygen release to tissues becomes impaired, rather than enhanced oxygen offloading or chloride shift.

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