If a person with a normally functioning immune system receives an organ transplant, which consequence follows relating to cellular rejection?

💡 Explanation

T-cell mediated graft destruction occurs because the recipient's T-cells recognize the transplanted organ's cells as foreign, triggering a cytotoxic immune response that destroys the graft. Therefore, T-cell activation causes rejection, rather than B-cell antibody production or NK cell hyperactivity, which play different roles in immune responses.

• An endurance athlete's cardiac output increases substantially during exercise. What distinguishes the mechanism enabling this increased output from the response in someone with advanced heart failure?
• Why does hyperkeratosis cause increased infection susceptibility in skin folds?
• An individual experiences recurrent luteal phase defects despite normal ovulation. Which compensatory mechanism masks the defect's impact on early pregnancy?
• Why does chronic hyperextension at the knee joint increase the risk of anterior cruciate ligament (ACL) injury during rapid deceleration?
• If a woman's luteal phase typically lasts only 7 days, which consequence is most likely, limiting the implantation window?
• A patient with pulmonary fibrosis has thickened alveolar membranes. Which mechanism explains why their blood oxygen saturation decreases even with supplemental oxygen?