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Human Body & Health

If a pharmaceutical company develops a new drug that acts as an agonist to a G-protein coupled receptor (GPCR) in pancreatic beta cells, which consequence follows?

A)Decreased glucagon secretion from alpha cells
B)Reduced glycogenolysis in liver hepatocytes
C)Upregulation of GLUT4 transporters in muscle
D)Increased insulin secretion into the bloodstream

💡 Explanation

GPCR agonists enhance receptor signaling, leading to increased intracellular signaling cascades that stimulate insulin release. Because activation of the receptor amplifies the normal insulin production pathway, insulin secretion increases; rather than decreasing glucagon, affecting glycogenolysis, or directly upregulating GLUT4 in muscle.

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