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Human Body & Health

If a researcher introduces antibodies that bind and neutralize a specific cytokine, such as TNF-alpha, during a chronic inflammatory response in a rheumatoid arthritis model, which consequence follows?

A)Increased T-cell activation persists
B)Reduced inflammation and tissue damage
C)Elevated complement pathway activation
D)Enhanced phagocytosis of immune complexes

💡 Explanation

The consequence is reduced inflammation and tissue damage because neutralizing TNF-alpha diminishes its pro-inflammatory signaling, thereby lessening the activation of inflammatory pathways and reducing immune cell infiltration. Therefore, the inflammatory response is dampened, rather than the other options that involve perpetuating inflammation.

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