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Life Sciences & Medicine

If a signaling molecule permanently disrupted a nuclear hormone receptor's ability to dimerize, which consequence follows?

A)Increased receptor binding to DNA
B)Enhanced mRNA transcript stability
C)Increased rate of protein translation
D)Impaired gene transcription regulation

💡 Explanation

Gene transcription regulation becomes impaired because dimerization is essential for nuclear hormone receptors to bind to specific DNA sequences and activate transcription factors. Therefore, impaired dimerization blocks this crucial signaling step, rather than increasing DNA binding, stability, or translation.

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