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← Human Body & HealthWhat causes bowing of leg bones in children affected by rickets?
A)Osteoclast hyperactivity degrades bone
B)Insufficient calcium phosphate mineralization✓
C)Increased collagen fiber deposition
D)Elevated parathyroid hormone reabsorption
💡 Explanation
Rickets causes bone deformities, such as bowed legs, because vitamin D deficiency leads to impaired calcium absorption. This results in insufficient calcium phosphate mineralization of the bone matrix, therefore bone softens under weight-bearing stress, rather than maintaining its rigid structure due to normal mineralization processes.
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