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← ScienceWhich bond cleavage outcome occurs when heating a chiral drug?
A)Racemization yields epimeric drug forms✓
B)Inversion only at activated stereocenters
C)Selective retention of desired conformers
D)Diastereomers form with covalent transfer
💡 Explanation
Racemization occurs because thermal energy overcomes the activation energy for chiral inversion via bond rotation yielding a racemic mixture due to homolytic cleavage, therefore racemization rather than selective retention is observed above this theshold.
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