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Which bond cleavage outcome occurs when heating a chiral drug?

A)Racemization yields epimeric drug forms
B)Inversion only at activated stereocenters
C)Selective retention of desired conformers
D)Diastereomers form with covalent transfer

💡 Explanation

Racemization occurs because thermal energy overcomes the activation energy for chiral inversion via bond rotation yielding a racemic mixture due to homolytic cleavage, therefore racemization rather than selective retention is observed above this theshold.

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