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โ Human Body & HealthWhich consequence occurs in prolonged Granulocyte Colony-Stimulating Factor (G-CSF) treatment?
A)Enhanced antimicrobial protection via phagocytosis
B)Reduced risk of autoimmune response
C)Diminished erythropoiesis in bone marrowโ
D)Augmented lymphocyte proliferation rates
๐ก Explanation
Prolonged G-CSF stimulates granulocyte production, leading to myeloid predominance that diminishes space for erythropoiesis due to niche competition โ a crowding-out effect. Therefore, erythropoiesis decreases, rather than the other options, because excess myeloid cells occupy space in the marrow.
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