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Which consequence results when a pharmaceutical drug excessively binds?

A)Off-target receptor activation occurs
B)Enhanced desired therapeutic efficacy
C)Reduced drug bioavailability results
D)Drug-target binding equilibrium favors release

💡 Explanation

Excessive binding causes off-target receptor activation, because the drug molecules saturate intended targets and then bind nonspecifically. This leads to unintended physiological effects, therefore side effects increase, rather than therapeutic effects, because increased bioavailability wouldn't drive such binding and prevents equilibrium disruption.

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