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← ScienceWhich consequence results when disulfide bridges are disrupted biochemically?
A)Protein misfolding and loss of function✓
B)Increased hydrophobic interactions with water
C)Enhanced stability at higher temperatures
D)Increased enzymatic hydrolysis of peptide bonds
💡 Explanation
Misfolding leads to a loss of function because disruption prevents the covalent cross-linking from stabilizing its folded state via disulfide rearrangement, therefore affecting protein folding. The protein unfoldeds rather than having its activity affected by temperature.
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