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← ScienceWhich consequence results when orthogonality fails between viral protein functions?
A)Uncontrolled protein aggregation occurs
B)Precise host pathway disruption fails✓
C)Enhanced immune system evasion happens
D)Therapeutic intervention gets amplified
💡 Explanation
Orthogonality ensures independent execution of functions, crucial for precise manipulation of host pathways. When orthogonality fails, proteins interact unpredictably via steric hindrance rather than specified binding because protein expression loses regulation; therefore pathway disruption is compromised, rather than evasion or therapy.
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