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← ScienceWhich consequence results when polypeptide torsion exceeds limits?
A)Protein misfolding due to steric hindrance✓
B)Increased hydrophobic interior exposure occurs
C)Hydrogen bonds formation is prohibited
D)Disulfide bridges formation is accelerated
💡 Explanation
Protein misfolding occurs through steric hindrance because exceeding normal torsion angles forces atoms too close; therefore, the native structure becomes energetically unfavorable, rather than hydrophobic exposure, that would cause aggregation under other pathways.
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