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← ScienceWhich consequence unfolds when a polymerase enzyme encounters abasic sites lacking hydrogen-bond donors?
A)Template replication errors increase✓
B)Frameshift mutations are attenuated
C)DNA polymerase processivity improves
D)Homologous recombination efficiency rises
💡 Explanation
Template replication errors increase during synthesis because the missing hydrogen-bond donor disrupts base pairing with the incoming nucleotide via Wobble base pairing, thereby lowering fidelity, rather than improving homology.
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