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Which consequence unfolds when a polymerase enzyme encounters abasic sites lacking hydrogen-bond donors?

A)Template replication errors increase
B)Frameshift mutations are attenuated
C)DNA polymerase processivity improves
D)Homologous recombination efficiency rises

💡 Explanation

Template replication errors increase during synthesis because the missing hydrogen-bond donor disrupts base pairing with the incoming nucleotide via Wobble base pairing, thereby lowering fidelity, rather than improving homology.

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