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Human Body & Health

Which endocrine imbalance results if human chorionic gonadotropin (hCG) declines rapidly during early pregnancy?

A)Progesterone deficiency, luteal insufficiency
B)Estrogen excess, endometrial hyperplasia
C)Androgen increase, virilization effects
D)Prolactin suppression, lactation failure

💡 Explanation

Rapid hCG decline reduces stimulation of the corpus luteum, thus the decreased progesterone causes "luteal insufficiency” and possible miscarriage. Therefore, progesterone deficiency results, rather than estrogen excess (B) or androgen/prolactin variations (C/D), because continued luteal support is crucial early in pregnancy.

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