Which limitation is bypassed when C4 plants spatially separate initial CO2 fixation before the Calvin cycle?

💡 Explanation

When C4 plants spatially separate CO2 fixation, the initial fixation by PEP carboxylase avoids the Calvin cycle's rubisco because it's prone to reacting with O2. Therefore, Rubisco inhibition by high oxygen, a disadvantage in C3 photosynthesis, is bypassed, rather than water need, transport limits, or stacking issues which are related processes.

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