Which mechanism explains why ovarian follicle atresia occurs during the reproductive cycle in humans?

💡 Explanation

Follicle atresia is driven by apoptosis of granulosa cells because these cells are essential for follicle development and hormone production. This regulated cell death eliminates follicles that are not selected for ovulation, therefore maintaining a balanced ovarian reserve, rather than allowing all follicles to mature or suppressing estrogen.

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