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Which mechanism limits peptide chain length during translation?

A)Premature termination through wobble pairing
B)Hydrophobic collapse decreases solvent accessibility
C)Ribosome stalling via mRNA hairpins
D)Accumulation of misfolded nascent protein

💡 Explanation

Ribosome stalling occurs through mRNA secondary structure impedence, restricting chain growth because translocation requires complete mRNA unwinding at the entry site. Therefore, ribosomal stalling limits chain length, rather than hydrophobic collapse or incorrect base pairing, which affect protein folding.

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