Which metabolic shift impairs brown adipose tissue function during arousal from hibernation?

💡 Explanation

During hibernation arousal, if glucose oxidation is pathologically enhanced over uninhibited lipolysis, normal thermogenesis from brown adipose tissue is impaired because UCP1 requires fatty acids to allow proton leak across the mitochondrial inner membrane. Therefore, enhanced glucose oxidation inhibits lipolysis rather than UCP1 decreasing or ketone production both require different pathways.

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