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Which outcome impairs enzyme function when exposed to heavy water?

A)Breaks correct hydrogen bonds
B)Inhibits disulfide bridge shuffling
C)Alters hydrophobic residue packing
D)Increases substrate binding affinity

💡 Explanation

Replacing protium (H) with deuterium (D) in enzymes will disrupt hydrogen bonding, a crucial element for protein folding and catalytic site structure; therefore, the enzyme’s activity decreases rather than improves because stability depends on precise configuration.

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