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Human Body & Health

Which outcome is caused by the increased resistance across demyelinated axons?

A)Decreased action potential propagation speed
B)Reduced astrocyte metabolic support signals
C)Increased oxygen diffusion into the tissues
D)Elevated concentration of synaptic glutamate

💡 Explanation

Demyelination increases axonal resistance, which lengthens the time constant during saltatory conduction, leading to slower action potential propagation because current leakage affects membrane depolarization. Therefore propagation slows, rather than faster propagation involving myelin sheath insulation.

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