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← ScienceWhich outcome limits peptide chain folding dynamics during protein formation?
A)Steric hindrance restricts bond rotation✓
B)Hydrophobic collapse mediates folding speed
C)Disulfide bridges accelerate protein maturation
D)Electrostatic repulsion promotes protein extension
💡 Explanation
Steric hindrance restricts bond rotation during protein folding due to the van der Waals radius around the bond preventing certain conformations; therefore, rotational freedom is limited, because bulky groups clash during peptide formation, rather than hydrophobic interactions dominating folding rate.
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