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Human Body & Health

Which outcome occurs in arteriosclerosis due to endothelium damage?

A)Increased platelet aggregation and thrombus formation
B)Decreased vascular permeability to plasma
C)Reduced LDL cholesterol deposition into plaques
D)Enhanced nitric oxide mediated vasodilation

💡 Explanation

Increased platelet aggregation therefore occurs rather than permeability decreasing, due to decreased nitric oxide linked to endothelial dysfunction promoting platelet activation. In arteriosclerosis, damage reveals collagen, initiating the coagulation cascade and thrombosis via platelet aggregation.

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