Which outcome occurs when a protein misfolds in vivo?

💡 Explanation

Aggregation occurs because protein misfolding triggers chaperone activity intended for refolding. These chaperones prevent aggregation via hydrophobic shielding, therefore, refolding is attempted, rather than immediate degradation or normal cellular processes if the folding was correct.

• Which outcome results when a fluid's increasing inertia overcomes intermolecular damping?
• Which consequence results when a racing car's diffuser exceeds its design Reynolds number?
• Which behaviour results when a dielectric exceeds its limit?
• Which outcome occurs when pump laser coherence degrades?
• Which consequence results when an aperture limits coherence?
• Which outcome occurs when solving Schrodinger's equation for a quantum dot with varying confinement potential functions?