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Human Body & Health

Which outcome occurs when cellular receptor tyrosine kinase signaling is continually stimulated by excessive growth factors?

A)Enhanced programmed cell death (apoptosis)
B)Decreased cellular metabolic rate
C)Reduced inflammatory cytokine production
D)Uncontrolled cell proliferation and tumor growth

💡 Explanation

Continued activation of receptor tyrosine kinase signaling bypasses normal regulatory checkpoints, promoting unchecked cell division and tumor formation, because the signaling cascades involved control cell cycle progression. Therefore, uncontrolled cell proliferation results, rather than apoptosis or reduced metabolic rate which are generally protective responses.

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