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← ScienceWhich outcome occurs when enzyme active-site shape changes?
A)Substrate binding affinity is altered✓
B)Cofactor concentration decreases rapidly
C)Competitive inhibition becomes impossible
D)Transition state energy barrier lowers
💡 Explanation
Substrate binding affinity shifts because the induced fit mechanism alters the active site’s geometry, therefore weakening or strengthening interaction; it is affinity, rather than activity changes via catalysis mechanisms, that is the focus here.
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