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← Nature & AnimalsWhich outcome occurs when ground squirrels enter hibernation with disrupted mitochondrial uncoupling protein 1 (UCP1)?
A)Increased reliance on shivering thermogenesis✓
B)Enhanced lipid metabolism efficiency
C)Suppressed inflammatory cytokine production
D)Improved core body temperature stability
💡 Explanation
Without UCP1's non-shivering thermogenesis, brown fat cannot produce heat efficiently, because the proton gradient is not bypassed. Therefore, the squirrel relies on shivering, rather than brown fat metabolism, to maintain some minimal metabolic temperature threshold. That temperature threshold facilitates survival.
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