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← Human Body & HealthWhich outcome occurs when receptor tyrosine kinase signaling for epidermal growth factor (EGF) is chronically activated in a cell?
A)Increased programmed cell death (apoptosis)
B)Decreased cell proliferation and growth
C)Enhanced cellular differentiation into specialized types
D)Uncontrolled cell division and tumor formation✓
💡 Explanation
Chronic activation of receptor tyrosine kinases, such as those for EGF, leads to sustained downstream signaling cascades that promote cell proliferation and survival. Because this overrides normal cell cycle control mechanisms, therefore uncontrolled cell division and tumor formation become likely, rather than apoptosis or controlled differentiation.
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