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← ScienceWhich outcome occurs when RNA polymerase encounters a transcription terminator hairpin loop in DNA template?
A)Polymerase translocation pausing and dissociation✓
B)Increased mRNA acetylation and translation
C)Intron splicing and exon ligation
D)DNA methylation suppressing translation initiation
💡 Explanation
When RNA polymerase encounters a hairpin loop, Rho-independent termination occurs because, due to the loop's stable structure, polymerase translocation pauses, weakening the DNA-RNA hybrid and causing dissociation. Therefore, transcriptional pausing and dissociation occur effectively stopping mRNA synthesis, rather than proceeding into other processes such as acetylation, splicing, or methylation which depend on other factors.
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