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← ScienceWhich outcome results following RNA polymerase stalling during transcription?
A)Transcriptional pausing triggers backtracking catalysis✓
B)Frameshift mutations become increasingly prominent
C)Protein degradation becomes kinetically favored
D)Ribosomal subunit assembly undergoes catastrophic failure
💡 Explanation
The pausing of RNA polymerase can cause it become unstable, therefore backtracking occurs because it allows the enzyme to correct errors by cleaving the nascent transcript; rather than causing mutations prematurely the pause corrects errors via kinetic proofreading.
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