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← Human Body & HealthWhich outcome results when a granulosa cell loses its ability to express aromatase during the mid-follicular phase?
A)Decreased estradiol synthesis locally✓
B)Enhanced androgen receptor sensitivity
C)Increased luteinizing hormone binding
D)Suppressed follicle-stimulating hormone secretion
💡 Explanation
Reduced aromatase hinders the conversion of androgens to estrogens (estradiol) in granulosa cells due to impaired steroidogenesis; therefore, local estradiol concentrations decrease rather than other hormonal cascades being directly affected; this impacts follicle maturation.
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