Which outcome results when C5 convertase dysfunction occurs in a localized infection?

💡 Explanation

Reduced opsonization occurs because C5 convertase cleaves C5, triggering opsonization via C5b deposition. Without efficient C5 convertase activity deposition is reduced, therefore pathogens are less efficiently phagocytosed, rather than an inflammatory response getting amplified.

• An individual's blood pressure consistently rises despite dietary changes. Which mechanism most likely explains why the ACE inhibitor drug, captopril, effectively reduces blood pressure in this scenario?
• Which outcome results when arterial compliance decreases due to calcification?
• Why does a chronic smoker with elevated carboxyhemoglobin levels experience impaired oxygen delivery to tissues during exercise, even if their hemoglobin concentration is normal?
• Which failure mode becomes likely in human musculoskeletal structure when fibroblast collagen production declines with age, leading to reduced collagen cross-linking within tendons?
• If a patient's gastric emptying rate increases dramatically due to vagus nerve stimulation, which consequence follows regarding the feedback loop involving GLP-1?
• If a patient with Hashimoto's thyroiditis experiences an infection, which consequence is most likely?