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Which process stabilizes protein molecular structure within the endoplasmic reticulum?

A)Disulfide bond formation between cysteine residues
B)Hydrophobic interactions with chaperone proteins
C)Glycosylation by oligosaccharyltransferase enzymes
D)Phosphorylation by protein kinase signaling cascades

💡 Explanation

When proteins fold, disulfide bond formation occurs because oxidation of cysteine sulfhydryl groups creates covalent links which correctly orient the tertiary structure and increase stability. Therefore structure is stabilised, rather than hydrophobicity, glycosylation or phosphorylation which are driven by different mechanisms.

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