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← ScienceWhich restriction arises during electron transport processes, leading to inhibited oxidative phosphorylation?
A)Proton gradient dissipation stalls ATP synthase✓
B)Complex I mutations yield cytochrome C
C)Ubiquinone depletion blocks electron acceptance
D)Cytochrome oxidase facilitates substrate level phosphorylation
💡 Explanation
When uncoupling proteins permeate the inner mitochondrial membrane protons bypass ATP synthase; the proton gradient collapses because chemiosmosis is interrupted. Therefore, ATP is not properly produced, rather than normal respiration driving phosphorylation.
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