Which risk increases as histamine secretion rises in airway mast cells of an asthmatic individual during allergen exposure?

💡 Explanation

Increased histamine secretion directly triggers bronchoconstriction in asthma because histamine binds to H1 receptors on bronchial smooth muscle, leading to contraction. Therefore, increased histamine levels elevate the severity of bronchoconstriction, rather than affecting eosinophil chemotaxis, alveolar surface tension, or macrophage activity.

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