Which risk increases when the injected substrate concentration overwhelms an enzyme's active site?

💡 Explanation

Excess substrate saturates the enzyme, meaning the reaction is limited to the rate of enzyme turnover, causing zero-order kinetics, because velocity is solely determined by total enzyme independent of substrate. Therefore, reaction displays zero order kinetics rather than normal kinetics because substrate is always in excess.

• Which outcome develops from elevated shear in centrifugal pumps?
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